Nonsteroidal anti-inflammatory agents, nonopioid analagesics
30mg/amp1 amp IM
MECHANISM OF ACTION:
- Inhibits prostaglandin synthesis, producing peripherally mediated analgesia
- Also has antipyretic and anti-inflammatory properties.
- Therapeutic effect:Decreased pain
Short term management of pain (not to exceed 5 days total for all routes combined)
- Cross-sensitivity with other NSAIDs may exist¨Pre- or perioperative use
- Known alcohol intoleranceUse cautiously in:
1) History of GI bleeding
2) Renal impair-ment (dosage reduction may be required)
3) Cardiovascular disease
SIDE EFFECTS/ ADVERSE EFFECTS:
2) abnormal thinking
1) GI Bleeding
2) abnormal taste
4) dry mouth
6) GI pain
2) renal toxicity
3) urinary frequency
1) prolonged bleeding time
1) injection site pain
1) allergic reaction, anaphylaxis
- Patients who have asthma, aspirin-induced allergy, and nasal polyps are at increased risk for developing hypersensitivity reactions. Assess for rhinitis, asthma, and urticaria.
- Assess pain (note type, location, and intensity) prior to and 1-2 hr following administration.
- Ketorolac therapy should always be given initially by the IM or IV route. Oral therapy should be used only as a continuation of parenteral therapy.
- Caution patient to avoid concurrent use of alcohol, aspirin, NSAIDs, acetaminophen, or other OTC medications without consulting health care professional.
- Advise patient to consult if rash, itching, visual disturbances, tinnitus, weight gain, edema, black stools, persistent headche, or influenza-like syndromes (chills,fever,muscles aches, pain) occur.
- Effectiveness of therapy can be demonstrated by decrease in severity of pain. Patients who do not respond to one NSAIDs may respond to another.